Wilson I. B. Onuigbo*

ABSTRACT

Original observation was to the effect that necrosis resulted among lung cancer cells when they were commingled with erythrocytes in the microenvironment of the thoracic duct. Therefore, I personally named this Factor as the “Erythrocyte Associated Necrosis Factor” (EANF). Can this hypothetical factor be recognized, as required logically, on the basis of its explanatory power? The answer was sought by outlining a puzzling undercurrent in metastases which needed to be tackled, seeing that it has largely been a problem in the literature, namely, cancer regression. Thereafter, answers were provided respectively in the light of the activities of the EANF. In all probability, the bountiful breakthrough in EANF research will point positively in the direction of that hoped for target therapy which could conduce to cancer cure. This particular feat will materialize just as when ominous bleeding was countered successfully because of the discovery and use of the Coagulation Factor.